Skullcap has been widely used for more than 2000 years against inflammatory skin conditions and as an anti-bacterial agent. It’s also employed in the case of illnesses like bronchitis and hay fever. Modern science has attributed to it a range of beneficial effects: anti-inflammatory1,2, anti-microbial3,4 and anti-oxidative5. Skullcap is also useful for sebum regulation6.
Li, BQ. et al. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Immunopharmacology.2000, 49(3):295-306.
Yang Ji et al. Identification of Baicalin as an Immunoregulatory Compound by Controlling TH17 Cell Differentiation. PLoS One. 2011, 6(2):e17164.
Novy P. et al. In vitro synergistic effects of baicalin with oxytetracycline and tetracycline against Staphylococcus aureus. J Antimicrob Chemother 2011; 66: 1298–1300.
Yang ZC. et al. The synergistic activity of antibiotics combined with eight traditional Chinese medicines against two different strains of Staphylococcus aureus. Colloids Surf B Biointerfaces. 2005, 25;41(2-3):79-81.
Wang X et al. Reassessment of antioxidant activity of baicalein in vitro. Asian J Pharm Biol Res 2011, 1, 186-194
6. Chen S et al. Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines. Cell Prolif. 2001 Oct;34(5):293-304.